Deaths,Programmed Cell
《英文msh詞典》Deaths,Programmed Cell
[入口詞] Deaths,Programmed Cell
[主題詞] Apoptosis
[英文釋義] One of the two mechanisms by which CELL DEATH occurs (the other being the pathological process of NECROSIS). Apoptosis is the mechanism responsible for the physiological deletion of cells and appears to be intrinsically programmed. It is characterized by distinctive morphologic changes in the nucleus and cytoplasm,chromatin cleavage at regularly spaced sites,and the endonucleolytic cleavage of genomic DNA; (DNA FRAGMENTATION); at internucleosomal sites. This mode of cell death serves as a balance to mitosis in regulating the size of animal tissues and in mediating pathologic processes associated with tumor growth.